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Single molecules dynamics of RNAs in live cells.

Contact-mediated gene expression control.

EM imaging of ER-mitochondria contacts.

Single molecules dynamics of RNAs in live cells.
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Molecular engineering
for cell biology &
biotechnology
Welcome to the Ngo Lab at Boston University!
We are interested in achieving a multi-scale understanding of the molecular organization of life. How do monomeric building blocks form macromolecules? and how do macromolecules give rise to organelles and cells? To address these questions, we use molecular engineering to probe and re-program how cells communicate with one another at cell-cell interfaces. We then leverage these tools to gain insight into natural biology and to overcome roadblocks in the development of cell therapies and tissue engineered systems.
A recent talk on our Synthetic Mechanobiology work can be viewed here: https://www.youtube.com/watch?v=SHvnViv3vJY&t=3s
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